Safety of injective immunotherapy with monomeric carbamylated allergoid given to pediatric patients with allergic rhinitis with/without asthma due to house dust mite
نویسندگان
چکیده
Background The safety and efficacy of Monomeric Carbamylated Allergoid in injections have been previously reported in adult patients. The aim of this case-series was to explore its safety in a paediatric populations. Monomeric Carbamylated Allergoids are chemically modified extracts characterized by hypoallergenic activity due to allergen lysines substitution and preserved structural conformation and size of the native allergen.
منابع مشابه
Safety and tolerability of ultra-rush (20 minutes) sublingual immunotherapy in patients with allergic rhinitis and/or asthma.
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Lais® allergoid tablets contain allergens that are modified by carbamylation. Due to their modified chemical structure, they are suitable for sublingual immunotherapy (SLIT) (13, 16, 17, 24). Based on their small molecule size of 12 to 40 kDa, they can be easily absorbed via the oral mucosa (1). In this review, we studied the efficacy of SLIT with carbamylated monomeric allergoid tablets in the...
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BACKGROUND Sublingual immunotherapy (SLIT) as a therapy for the treatment of allergic rhinitis in children might be acceptable as an alternative for subcutaneous immunotherapy. However, the efficacy of SLIT with house dust mite extract is not well established. OBJECTIVE To investigate whether SLIT in house dust mite-allergic children recruited in primary care is effective and safe. METHODS ...
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Allergic rhinitis is estimated to affect 10%-20% of pediatric population and it is caused by the IgE-sensitization to environmental allergens, most importantly grass pollens and house dust mites. Allergic rhinitis can influence patient's daily activity severely and may precede the development of asthma, especially if it is not diagnosed and treated correctly. In addition to subcutaneous immunot...
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عنوان ژورنال:
دوره 8 شماره
صفحات -
تاریخ انتشار 2015